Bayer Procox Oral Suspension 7.5 ml

Suspension for dogs and puppies Bayer Procox Dog Puppy against worms 7.5 ml

Bayer Procox oral suspension against worms, 7.5 ml

Bayer (Bayer) Procox 7.5 ml.

Composition:

1 ml of suspension contains active ingredients:

emodepside - 0.9 mg,

toltrazuril - 18 mg.

Excipients: butylated hydroxytoluene (E321), sorbic acid (E200).

Pharmacological properties:

ATS vet: QP52AX60, endoparasitic veterinary drugs

The endoparasitic effect of the suspension is due to the characteristics of the active ingredients emodepside and toltrazuril.

Emodepsid is an endoparasitocide, belongs to the group of depsipeptides. Emodepside excites the presynaptic latrophilin nerve receptors of gastrointestinal nematodes, which leads to their paralysis and death.

Toltrazuril – endoparasitocide, acts against eimeria of the genera Eimeria and Isospora. Toltrazuril is effective against all intracellular stages of eimeria development at the stages of merogony (asexual reproduction) and gametogony (sexual phase), the action of toltrazuril is eimeriocidal.

Pharmacokinetics

After oral use of the drug, emodepside is transported to all organs, its highest concentration is detected in adipose tissue. The main products of metabolism are unchanged emodepside and hydroxyl derivatives. Toltrazuril is slowly absorbed after oral use. The main metabolite is toltrazuril sulfone. The maximum concentration of emodepside and toltrazuril is detected after 2 hours and after 18 hours, respectively.

Application

Treatment and prevention of dogs affected by mixed infestations caused by gastrointestinal nematodes (mature and immature adults, L4 larvae of Toxocara canis, mature adults of Uncinaria stenocephala, mature adults of Ancylostoma caninum) and eimeria (Isospora ohioensis complex, Isospora canis).

To stop the reproduction of eimeria and the release of oocysts into the external environment.

Treatment of animals with the drug slows down the spread of eimeriosis, but is not an effective treatment for clinical manifestations of the disease.

Dosage

The recommended minimum dose of the drug is 0.5 ml of suspension / kg body weight, which is equivalent to 0.45 mg emodepside / kg body weight and 9 mg toltrazuril / kg body weight. Recommended doses of the drug are given in the table:

Body weight (kg)	Dose (ml)
0.4	0.2
> 0.4 0.6*	0.3
> 0.6 0.8	0.4
> 0.8 1.0	0.5
> 1.0 1.2	0.6
> 1.2 1.4	0.7
> 1.4 1.6	0.8
> 1.6 1.8	0.9
> 1.8 2.0	1.0
> 2.0 2.2	1.1
> 2.2 2.4	1.2
> 2.4 2.6	1.3
> 2.6 2.8	1.4
> 2.8 3.0	1.5
> 3.0 3.2	1.6
> 3.2 3.4	1.7
> 3.4 3.6	1.8
> 3.6 3.8	1.9
> 3.8 4.0	2.0
> 4 5	2.5
> 5 6	3.0
> 6 7	3.5
> 7 8	4.0
> 8 9	4.5
> 9 10	5.0
>10 kg: use 0.5 ml suspension/kg body weight

*=from 0.4 to 0.6 kg.

Single use. In case of nematode infestation, repeat treatment after 14 days. Before use, shake the bottle with the drug and open the cap. Turn the bottle with the drug upside down and draw the suspension to the required level into a disposable syringe. Turn the bottle with the drug into a vertical position and pull out the syringe. Inject the suspension with a syringe directly into the animal’s oral cavity (per os). To administer the drug to an animal, use a new syringe each time (it is impossible to reuse the syringe).

Contraindications:

Do not use on puppies under 2 weeks of age and dogs weighing up to 0.4 kg. Do not use in animals with increased sensitivity to the components of the drug.

Do not use in females during pregnancy and the first 2 weeks of lactation.

Caution:

When fighting eimeriosis in animals, a whole range of measures must be developed aimed at eliminating the pathogen; treating animals with Procox is one of such measures. In dog kennels, when clinical signs of eimeriosis recur, each offspring must be treated with the drug Procox. Treatment must be carried out over a long period of time. All dogs at risk of infection should be treated at the same time, including adult animals, as they may be subclinically ill.

Puppies of Collie breeds and their crosses may have hypersensitivity to the drug Procox. The use of the drug in emaciated animals, as well as with liver and kidney diseases, should be based on an assessment of the risk and the need for treatment.

When treating animals with Procox, do not eat, drink or smoke. After handling the product, wash your hands thoroughly with soap and water. If the drug gets on your skin, wash it off immediately with soap and water. In case of contact with eyes, rinse immediately with plenty of water. If the drug is accidentally swallowed, consult a doctor and show the package insert or label of the drug.

Issue form:

Glass bottles of yellow color with a polypropylene cap with protection against accidental opening, 7.5 ml, packed in cardboard boxes.

Storage:

Store closed and packaged in a dry place, inaccessible to children and animals, separately from food and feed, at a temperature of 0 to 30 ⁰C.

Shelf life - 2 years. Shelf life after opening the bottle is 10 weeks.