AnimAll VetLine Spot-On drops for dogs 40–60 kg, 10 ml are antiparasitic spot-on drops from the Ukrainian brand AnimAll. Each ml contains three active ingredients: permethrin 25%, imidacloprid 10% and pyriproxyfen 2%. The drops protect dogs against fleas, sucking lice, chewing lice and ixodid ticks, as well as sarcoptic mange and ear mites. One treatment lasts 4 weeks. The 10 ml pipette is one treatment for a dog weighing 40 to 60 kg.
How the three ingredients work
Imidacloprid kills fleas, sucking lice and chewing lice. Permethrin acts on ticks and repels parasites — according to the manufacturer, the repellent effect lasts up to 4 weeks. Pyriproxyfen is an insect growth regulator: it stops flea eggs and larvae from developing, so the parasite population in the home doesn't recover. Insects on the dog die within 12 hours of treatment, and ticks die or drop off within 48 hours. The spectrum includes ixodid ticks (Ixodes, Dermacentor, Rhipicephalus, Hyalomma, Haemaphysalis), the mange mite Sarcoptes canis and the ear mite Otodectes cynotis.
Key specs
| Parameter | Value |
|---|---|
| Per 1 ml | permethrin 25%, imidacloprid 10%, pyriproxyfen 2% |
| Dog weight | 40–60 kg |
| Dose | 10 ml (the whole pipette) |
| Protection | 4 weeks |
| Age | puppies from 9 weeks and 1.5 kg |
| Shelf life | 3 years |
Pros
- Three ingredients. Fleas, ticks and flea larvae development all under control.
- Broad spectrum. Including mange and ear mites.
- Fast action. Insects die within 12 hours, ticks within 48.
- Repellent. Repels parasites for up to 4 weeks.
- Rainproof. The drops stay effective even if the coat gets wet.
- Affordable for big dogs. One pipette covers a dog up to 60 kg.
Cons
- Lethal to cats. Permethrin is toxic to cats — dogs only.
- Contraindications apply. Not for puppies under 9 weeks or for sick, emaciated or very old dogs.
- No swimming for 48 hours. After treatment, keep the dog out of ponds and rivers.
- Monthly treatment. Miss one and your dog is unprotected.
How to apply
Apply the drops to intact, dry skin. Holding the pipette upright, snap off the tip, part the coat and squeeze the product onto the skin. For large dogs, apply it in 3–4 spots along the spine — from the withers to the tail — in places the dog can't lick. Keep it away from the eyes, mucous membranes and mouth. Don't let a freshly treated dog have contact with other animals, and keep it out of open water for 48 hours. If your dog needs a shampoo bath, the manufacturer advises doing it 3 days before treatment. Repeat once a month.
Why it's dangerous for cats
Permethrin, safe for dogs at the correct dose, causes severe poisoning in cats: tremors, seizures, drooling — and it can be fatal. Never apply dog drops to a cat, and don't let a cat rub against a freshly treated dog until the application site is dry. On protecting cats, see fleas on a cat: how to get rid of them.
Dosing by weight
AnimAll VetLine Spot-On comes in different weight bands: 1.5–4 kg — 0.8 ml, 4–10 kg — 2 ml, 10–20 kg — 4 ml, 20–30 kg — 6 ml, 30–40 kg — 8 ml, 40–60 kg — 10 ml. Always choose the pipette by your dog's weight. A similar permethrin–imidacloprid combination is found in Advantix and KRUG Pet Dog; if you'd prefer long-term protection, see the AnimAll VetLine collar. Protection methods are compared in drops, tablets or a collar.
Who it suits
Large dogs weighing 40–60 kg for monthly protection against fleas, ticks and lice, and for mange and ear mites — especially in homes without cats. Pregnant and nursing females should be treated only after consulting a vet. More products are in the antiparasitic products section.
Verdict
AnimAll VetLine Spot-On 40–60 kg is an affordable three-ingredient spot-on: permethrin and imidacloprid protect against ticks and fleas, and pyriproxyfen stops flea larvae from developing. A month of protection, fast action and rain resistance. The key points: treat monthly, follow the weight bands and never use it on cats.
FAQ
How long do the drops last?
One treatment protects against fleas and ticks for 4 weeks.
What weight is this pipette for?
Dogs of 40–60 kg; the dose is 10 ml.
Can it be used on a cat?
No, permethrin drops are dangerous for cats.
When do ticks die?
Insects within 12 hours; ticks die or detach within 48 hours.
Can the dog be bathed after treatment?
No swimming for 48 hours; shampoo baths are best done 3 days before treatment.
Do the drops help with ear mites?
Yes, Otodectes cynotis is within the spectrum.
Can a pregnant dog be treated?
According to the manufacturer, yes, but only after consulting a vet.



