ZooHealth Vormikil Dewormer Tablet №1

Broad-spectrum anthelmintic drug for animals UZVPPostach ZooHealth Wormikil 1 tablet

Flat cylindrical scored uncoated tablets, yellow, odourless.

Composition

1 tablet (0,5 g) contains the active substances:

pyrantel pamoate (embonate) - 144 mg;

praziquantel - 50 mg.

Excipients: powdered sugar, starch, calcium carbonate.

Pharmacological properties

ATCvet QP52, veterinary anthelmintics (QP52AA01, praziquantel; QP52AF02, pyrantel)

The anthelmintic spectrum of Vormikil is based on the pharmacological action of its components, pyrantel pamoate and praziquantel.

Pyrantel pamoate (embonate) is active against nematodes (roundworms); it acts on their cholinergic receptors, causing irreversible spastic paralysis. Dead nematodes are expelled from the animal's body by the peristaltic movements of the intestine. However, pyrantel is not active against migrating larval stages of helminths.

In mammals, pyrantel is poorly absorbed in the digestive tract, and after oral administration per os at a dose of 10 mg/kg of body weight its plasma concentration is 0,005-0,13 mcg/ml after 1-3 h. Pyrantel absorbed into the bloodstream is partly metabolised in the liver to N-methyl-1,3-propanediamine.

Praziquantel is active against cestodes (tapeworms); it is rapidly absorbed through the entire surface of the parasites and distributed evenly throughout the body. Praziquantel increases membrane permeability to calcium ions and causes increased muscle activity, followed by contraction and spastic paralysis, and destroys the outer cuticle of adult cestodes. In some cases tapeworms are completely digested by the enzymes of the digestive system and are not found in the faeces.

In mammals, praziquantel is rapidly absorbed in the digestive tract. Its peak plasma concentration is reached 1-2 hours after administration; it is rapidly metabolised, and up to 80% is excreted as metabolites by the kidneys within 4 days, with 90% excreted in the first 24 h.

Indications

Deworming of dogs and cats with nematodoses (Toxocara canis, Toxocara cati, Toxascaris leonina, Ancylostoma spp., Uncinaria spp., Trichuris spp.) and cestodoses (Dipylidium caninum, Echinococcus multilocularis, Taenia spp., Mesocestoides spp.).

Dosage

Orally: the tablets are placed directly on the root of the animal's tongue or given crushed with food at the following doses:

The recommended dose is 1 tablet per 10 kg of the animal's body weight, once, without fasting.

Animals are dewormed every quarter. Preventive treatments are also recommended 2-4 weeks before the planned mating date.

Kittens and puppies can be dewormed from 30 days of age.

Contraindications

Hypersensitivity to the components of the product.

Do not use in sick and emaciated animals or animals with liver disease.

Warnings

Do not use simultaneously with other antiparasitic products.

Presentation

Blisters of 10 tablets, cardboard boxes of 2 blisters.

Polyethylene jars with lids of 20, 50 and 100 tablets

Storage

Store in the original packaging separately from food and feed at a temperature of 2 to 30°C and relative humidity of no more than 75%.

Shelf life - 2 years.