Krug Antizud for large dogs, 20 ml is a herbal oral emulsion used for inflammatory and allergic skin conditions in dogs weighing over 20 kg: urticaria, atopic dermatitis, eczema and neurodermatitis. Plant extracts make up 30%: celandine, plantain, valerian root, three-lobe bur marigold, heartsease and liquorice root. The course lasts 12 days: 4 days at the full dose, then 8 days at half. The pack contains two 10 ml dosing syringes.
What it is and who makes it
Krug is a Ukrainian maker of feed supplements and herbal products for animals. Antizud comes in several versions by dog size; this one is for large dogs. It's a herbal product: plants with anti-inflammatory, anti-allergic and calming effects are combined in one emulsion that's easy to dose by syringe.
Ingredients
| Plant | Traditional use |
|---|---|
| Three-lobe bur marigold, heartsease | Skin rashes, itching, eczema |
| Celandine | Anti-inflammatory action on the skin |
| Plantain | Healing, anti-inflammatory |
| Liquorice root | Anti-allergic action |
| Valerian root | Calming, reduces stress-related scratching |
The rest is soy lecithin, xanthan gum, deodorised oil and water.
Dosage
| Dog weight | First 4 days, per day | Next 8 days, per day |
|---|---|---|
| 20–30 kg | 1.6 ml | 0.8 ml |
| 30–40 kg | 2.0 ml | 1.0 ml |
| Over 40 kg | 2.4 ml | 1.2 ml |
Shake the syringe and give the emulsion in the morning with a meal, mixed into a little food or at the back of the tongue. Avoid missed doses — they reduce effectiveness.
Pros
- Herbal formula. Suits owners who want to start with gentle products.
- Combined action. Herbs against inflammation, allergy and stress scratching.
- Accurate dosing. A dosing syringe and a weight-based schedule.
- Short course. 12 days.
- Affordable. A Ukrainian product.
Cons and what to keep in mind
- Weaker than steroids and prescription drugs. For severe itching, a vet may prescribe other treatment.
- Doesn't treat the cause. Fleas, mites, fungus and food allergy need their own treatment.
- Restrictions. Not recommended in pregnancy, lactation or for puppies under 8 weeks.
- Large dogs only. Small and medium dogs need another version.
- Distinctive smell. Easier to mix with food.
Why dogs itch
Fleas are ruled out first: even a few bites cause severe itching in allergic dogs. Treat the dog and the home — more in fleas and ticks in dogs. If itching persists, a vet checks the skin for mites, fungus and bacteria and, if food allergy is suspected, prescribes a diet — see hypoallergenic dog food.
Herbal or prescription
Herbal products suit mild to moderate itching and support between flare-ups. With marked itching, scratching to the point of wounds or weeping skin, a vet may prescribe prescription drugs — for example, Apoquel tablets or Cortavance spray. Don't combine different anti-itch products without a vet's agreement.
Who it suits
Large dogs over 20 kg with mild to moderate itching from allergic or inflammatory skin conditions, and owners who prefer herbal products. Other supplements are in vitamins and mineral supplements.
Verdict
Krug Antizud is an affordable herbal emulsion for large dogs with a clear 12-day schedule and a handy syringe. It helps with mild to moderate itching but doesn't replace finding the cause or prescription treatment in severe cases.
Skin care during the course
While your dog is taking the emulsion, help the skin from the outside: wash with a gentle sensitive-skin shampoo no more than once every 1–2 weeks, and dry the coat thoroughly, especially in skin folds and between the toes. Avoid treats with new proteins so you don't trigger allergies. If your dog scratches one spot raw, use a protective cone and see a vet. Keep a simple diary of how often your dog scratches morning and evening — it makes it easier to judge the effect of the course.
Frequently Asked Questions
How much Antizud for a 35 kg dog?
2 ml a day for the first 4 days, then 1 ml for another 8 days.
When should it be given?
In the morning with a meal.
How long is the course?
12 days.
Can a pregnant dog have it?
It isn't recommended.
Is it suitable for a small dog?
This version is for dogs over 20 kg; there's a separate pack for small dogs.
Is it a steroid?
No, it's a herbal emulsion.



