UZVPP ASD-2U Solution 50 ml

Antiseptic-immunostimulator UZVPP ASD-2U 50 ml

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Dorogov's antiseptic stimulator fraction 2 for farm animals ASD - 2F

Composition and pharmacological properties.
It contains carboxylic acids, aliphatic hydrocarbons, amines and amides, alkylbenzenes and substituted phenols, compounds with an active sulfhydryl group, etc., as well as water.

When taken orally, it has an activating effect on the central and autonomic nervous systems, stimulates gastrointestinal motility and the secretion of the digestive glands, increases the activity of digestive and tissue enzymes, improves the passage of Na+ and K+ ions through cell membranes and helps normalise digestion, nutrient absorption and the body's natural resistance.

When applied externally, the product stimulates the activity of the reticuloendothelial system, normalises trophism and speeds up the regeneration of damaged tissues; it has a pronounced antiseptic and anti-inflammatory effect.

Indications.
«Dorogov's antiseptic stimulator fraction 2» («ASD-2F») is prescribed for farm animals, poultry and carnivores for the prevention and treatment of diseases of the gastrointestinal tract, respiratory organs and urogenital system, skin lesions and metabolic disorders, to stimulate the central and autonomic nervous systems, to increase natural resistance in weakened animals and those that have recovered from infectious and parasitic diseases, and to stimulate the growth and development of young farm animals and poultry.

Contraindications.
Individual hypersensitivity of the animal to the components of the product.

Dosage and administration.

Orally, "ASD-2F" is given to animals with drinking water before feeding.

Externally, "ASD-2F" is used as 15–20% solutions prepared with sterile saline or boiled water. When preparing a treatment solution of the required concentration, the original sterile "ASD-2F" solution is taken as 100%.

Cows.
For vaginitis and retained placenta (after its removal), a 3-5% "ASD-2F" solution warmed to 40°C is used to rinse the vagina once a day for 4-5 days, using 1.5-2 l of solution per treatment. If the cervix is open, 200-300 ml of the solution is introduced into the uterus and removed immediately.

For acute and chronic endometritis, myometritis and pyometra in cows, if the cervix is open, 200-300 ml of a 15% "ASD-2F" solution warmed to 40°C is introduced into the uterine cavity and removed immediately. A catheter with a return flow of liquid is used for this. The treatment is carried out once a day for 4–5 days. For trichomoniasis in cows, in addition to etiotropic treatment, a 20% "ASD-2F" solution is introduced into the vagina using a Janet syringe with a rubber tube and a special catheter with many holes at the end. Treatment is carried out once a day for 5-7 days, using 200-300 ml of solution per procedure.

In the treatment of bulls with acute trichomoniasis, in addition to etiotropic treatment, the preputial sac is rinsed with a 2-3% "ASD-2F" solution, introduced in an amount of 0.5-1.0 l through a catheter connected by a rubber tube to an Esmarch mug. After that, the external opening of the preputial sac is held closed by hand for 3-5 minutes and a light massage is given. Treatment is carried out once a day for 5-7 days.

For bloat in cattle, "ASD-2F" is given to drink or introduced into the rumen through a stomach tube once or twice a day at the single dose shown in table 1, but for no more than 3 days. During treatment, warm enemas, rumen massage and other procedures provided for this condition are prescribed.

To increase the body's resistance to adverse environmental factors, increase weight gain and reduce mortality, "ASD-2F" is given to calves – with milk or drinking water at 0.1 ml of "ASD-2F" per 1 kg of body weight every other day for 1–2 months.

For piglets, the product is given individually mixed with compound feed at 0.1 ml of "ASD-2F" per 1 kg of body weight from 7 days to 2 months of age;

For catarrhal pneumonia, dyspepsia, gastroenterocolitis and gastroenteritis, in addition to etiotropic treatment, "ASD-2F" is given to piglets once a day with drinking water 30-40 minutes before feeding at the doses shown in table 1. Treatment is carried out in 5-day courses with an interval of 2-3 days until recovery.

For intestinal flatulence in horses, "ASD-2F" is given to drink or introduced through a stomach tube once at the doses shown in table 1.

During treatment, warm enemas, abdominal massage and other procedures provided for this condition are prescribed. If necessary, the treatment is repeated. For strangles in horses and abscesses in the submandibular space and on other parts of the body, after preliminary cleaning, the abscess cavities are rinsed with a 15-20% "ASD- 2F" solution, or tampons soaked in the solution are inserted into them once a day for 7–9 days until the wound is free of pus and granulation appears. For dyspepsia, gastroenterocolitis, gastroenteritis and dystrophic conditions caused by digestive and metabolic disorders, "ASD-2F" is given orally once a day at the single doses shown in table 1. Treatment is carried out in 5-day courses with an interval of 2-3 days until the animal recovers. To stimulate the central and autonomic nervous systems, increase resistance in animals that have recovered from infectious and parasitic diseases and speed up skin healing, as well as for necrobacillosis, eczema, dermatitis and trophic ulcers, "ASD-2F" is given with drinking water once a day at the doses shown in table 1. Treatment is carried out in 5-day courses with an interval of 3 days until recovery.

Table 1. Doses of "ASD-2F".
Animal species
Age of animal
Volume of ASD-2F, ml
Volume of water, ml
Cattle
3 years and older
20-30
200-400

from 1 year to 3 years
10-15
100-400

up to 1 year
5-7
40-100
Sheep
one year and older
2-5
40-100

from 6 months to 1 year
1-3
20-80

up to 6 months
0,5-2
10-40
Horses
3 years and older
10-20
200-600

from 1 year to 3 years
10-15
200-400

up to 1 year
5
100
Pigs
one year and older
5-10
100-200

from 6 months to 1 year
2-5
40-100

2-3 months
1-3
20-80
Dogs
older than 6 months
2
40

Infected, slow-healing wounds are rinsed with a 15-20% "ASD-2F" solution, after which a dressing soaked in this solution is applied. Treatment is carried out 1–2 times a day for 4–5 days until the wound is free of pus. In case of fistulas, opened abscess cavities or phlegmons, a gauze drain soaked in the solution is inserted into the cavity and covered with a sterile dressing. The drain is changed daily until a granulation ridge forms.

In poultry, the product is used to increase the body's resistance, support the formation of immunity and stimulate growth and development, as well as for apteriosis and for the treatment and prevention of gastrointestinal and respiratory diseases. To increase egg production and prevent ovariosalpingitis. Dosing schedules and doses are shown in table 2.

Table 2. Use of "ASD-2F" in poultry farming.

Indications for use
Dose of "ASD-2F"
Schedule
For day-old chicks, to increase resistance and support the development and formation of immunity
35 ml per 100 l of drinking water
7 days in a row, then 2 days before and 2 days after vaccination
For chicks, poults, ducklings and goslings, to stimulate growth; for apteriosis
5 ml of a 10% aqueous solution per 1 m3 of poultry house
As an aerosol at 1, 10, 28 and 38 days of age; exposure – 15 min.
To prevent gastrointestinal diseases and increase resistance
3 ml per 100 birds (15 ml of "ASD-2F" per 100 l of water)
With drinking water for 7 days in a row
For respiratory diseases, including infectious laryngotracheitis, infectious bronchitis of chickens, respiratory mycoplasmosis and colisepticaemia
young birds – 10 ml per 1000 birds (5.0 ml of "ASD- 2F" per 100 l of water); adult flock – 30 ml per 1000 birds (15 ml of "ASD-2F" per 100 l of water)
With water for 5 days in a row
For laying hens, to prevent ovariosalpingitis and increase egg production
35 ml per 100 l of drinking water
With water for 5–7 days in a row
For chicks, to stimulate growth and development
0.1 ml per 1 kg of bird body weight
With water every other day for 1–2 months

Adverse effects.
As a rule, no adverse effects or complications are observed.

Special instructions.
The product does not rule out the use of other medicines for specific or symptomatic therapy.

Milk from dairy animals and eggs from poultry can be used without restrictions after use of the product. In case of forced slaughter, the meat can be used without restrictions.

Storage.
Store in the manufacturer's closed packaging away from food and feed, protected from light, at a temperature of 4°C to 35°C.
Shelf life, if storage conditions are observed, – 3 years from the date of manufacture. After opening the primary packaging - 30 days.